Endocannabinoid system & Cannabis
The scientific basis
The endocannabinoid system constitutes one of the most underappreciated regulatory mechanisms of human physiology. Despite the rapid expansion of the relevant literature over recent decades, the understanding of its function and the rational use of cannabis in medical practice remain fragmented, often confused, and frequently burdened by ideological bias. The purpose of this website is to support a work that seeks to clarify this field on strictly scientific grounds.
Public discourse on cannabis typically oscillates between two equally inadequate extremes. On one side lies a romanticised idealisation of “naturalness”, which substitutes pharmacology with slogans. On the other side persists an indiscriminate demonisation that fails to distinguish between molecules, mechanisms, dosage, indications, and risks. Both approaches diverge from what medical reasoning requires: discrimination, proportion, and evidence.
The book Endocannabinoid system and Cannabis—The scientific basis was written precisely to address this confusion. It examines the biology of the endocannabinoid system, the principal phytocannabinoids, their metabolites, receptors, and enzymes, as well as the range of potential therapeutic applications, without concealing either the limitations or the uncertainties of current knowledge. The objective is not to promote a trend, but to restore scientific order to a field where noise often exceeds signal.
This website functions as a companion to the book. Here, the reader may find essential information about the work, access to the introduction, selected excerpts, and direct links for acquisition. The intention is to facilitate an initial, serious, and properly oriented engagement with the subject before deeper study of the full text.
The work is addressed primarily to healthcare professionals, but also to readers who wish to approach the subject of cannabis not through slogans, but through biology, pathophysiology, and clinical reasoning. In an era in which terms such as “medical cannabis” and “cannabinoids” are frequently used without precision, the need for a clear scientific foundation is more pressing than ever.
